How does CRISPR/Cas gene editing work?
A powerful tool for changing
the genome in living cells
CRISPR/Cas is used to modify an organism's DNA at a precise location. To do this, a short, customizable guide RNA is used to target a Cas protein to a specific DNA sequence. Scientists can specify the sequence of the guide RNA, allowing them to program where in the genome the modification will occur.
New: Chopped! CRISPR/Cas9 Learning Lab
Use the CRISPR/Cas9 system in vitro to target and cut DNA in a test tube!
Visualize your results through an easy gel electrophoresis readout.
Conduct a gene targeting experiment quickly and easily using the molecular components of the CRISPR/Cas gene editing system in a test tube. No need for living cells or complicated equipment!
Knockout! A CRISPR/Cas Gene Targeting Lab
Become a genome engineer!
Knock out a gene using the CRISPR/Cas system
Want to learn more about the Knockout! lab? Check out our video.
Use the CRISPR/Cas system to knock out a gene in bacteria in as little as one class period and see a phenotypic change the next day. This lab is easy for teachers to prepare and simple for students to perform, and using CRISPR/Cas technology packs a powerful punch!