How does CRISPR/Cas gene editing work?
A powerful tool for changing
the genome in living cells
CRISPR/Cas is used to modify an organism's DNA at a precise location. To do this, a short, customizable guide RNA is used to target a Cas protein to a specific DNA sequence. Scientists can specify the sequence of the guide RNA, allowing them to program where in the genome the modification will occur.
Knockout! A CRISPR/Cas gene targeting lab
Become a genome engineer!
Knock out a gene using the CRISPR/Cas system
Want to learn more about the Knockout! lab? Check out our video.
Use the CRISPR/Cas system to knock out a gene in bacteria in as little as one class periods and see a phenotypic change the next day. This lab is easy for teachers to prepare and simple for students to perform, and using CRISPR/Cas technology packs a powerful punch!
CRISPR/Cas resource library
Reagents to perform experiment twice
Available Spring 2021
Reagents for 8 lab groups