Exploring genotype-phenotype mismatches in the PTC Taster Lab
In this short video, we explore an interesting wrinkle in the PTC Taster Learning Lab: what is happening when a student’s taster phenotype doesn’t align with their TAS2R38 genotype? While most students will see a clear match between their genotype and their ability to taste PTC, a small minority may not — offering you a valuable opportunity to discuss the complexities of gene expression. This video helps frame PTC tasting not just as a straightforward Mendelian trait, but as a jumping-off point to explore how environment, other genetic factors, and even something as simple as saliva can influence phenotype. It’s a helpful resource for deepening students’ understanding of what genotype-phenotype relationships really look like.
This video is part of the PTC Taster Digital Lab. Create a free miniPCR Digital account to explore this learning activity in its entirety.
