Visualize Real DNA Structure and Base Pairing in Your Hands with the DNA Glow Lab
An engaging, hands-on lab activity to teach the fundamentals of DNA structure
DNA structure and complementary base pairing are essential concepts in biology, but there are very few, if any, authentic hands-on lab activities to engage students with this content. The DNA Glow Lab from miniPCR bio lets you move beyond static DNA models and visualize DNA in action!
Deepen your students’ understanding of base pairing and DNA structure with a visually eye-catching hands-on experiment! This lab uses a fluorescent dye that only glows when bound to double-stranded DNA. Get clear readouts as students compare dim, denatured single-stranded DNA to glowing double-stranded DNA. While experimenting with different variables, students observe DNA base pairs forming and then splitting in real time!

Students manipulate DNA structure with fluorescent visual outputs
With this lab, key concepts like base pairing, annealing, and denaturation come to life with bright, visible outputs.
Implementation is easy; students only need a micropipette, heat block, and the affordable, easy-to-use P51™ Molecular Fluorescence Viewer. View your fluorescent results in the palm of your hand!
Features of the DNA Glow Learning Lab:
- Teach DNA structure and complementary base pairing, hands-on!
- Free curriculum designed to increase student engagement and understanding. Can be completed in a 45-minute class period
- Minimal equipment requirements: P51™ Molecular Fluorescence Viewer, 96 °C heat source, 2-20 μl micropipette
Ready to teach DNA structure hands-on? Download the DNA Glow Lab curriculum today! Access the full Instructor’s guide, editable classroom PowerPoint slides, and more under the “Curriculum downloads” tab.
Bring the DNA structure to life for your students with this engaging hands-on lab!

