Looking for biotechnology labs that align to the AP Biology Frameworks?

Looking for how miniPCR bio Learning Labs align to the AP biology frameworks? Check out our full list of AP Biology-aligned Learning Labs from miniPCR bio™.

Biotechnology may be listed as topic 6.8 in the AP Biology Course and Exam Description, but really, biotechnology is not a standalone unit. Biotechnology is integral to how biologists do science. As you train your AP students to answer biological questions, you want them to use the tools of modern biology!

At miniPCR bio, we offer inquiry-based, hands-on lab investigations for all eight units covered on the AP Biology exam. All our labs invite students to investigate natural phenomena, carry out experiments to test predictions, collect and analyze data, interpret the data to draw conclusions, and develop a scientific claim with the evidence they collected via modern techniques.

To see how our Learning Labs align to the AP Biology units, see the table below. Click on any of the lab titles to learn more about it.

Full list of AP Biology aligned Learning Labs from miniPCR bio 1. Chemistry of Life 2. Cell Structure and Function 3. Cell Energetics 4. Cell Communications and Cell Cycle 5. Heredity 6. Gene Expression and Regulation 7. Natural Selection 8. Ecology
miniPCR® Crime Lab: Missy Baker Missing™ KT-1000-03
GMO Detection Lab KT-1003-01
Genotype to Phenotype: PTC Taster Lab KT-1004-03
miniPCR Sleep Lab™ – Lark or Owl? KT-1005-01
miniPCR® Antibiotic Resistance Lab: Monitoring resistant organisms in the environment KT-1010-01
Plant Genetics Lab: Taking Mendel Molecular with Wisconsin Fast Plants® KT-1011-01
eDNA Project: Sampling Soil for Antibiotic Resistance KT-1012-02
Sickle Cell Genetics Lab: Diagnosing Baby Marie™ KT-1502-01
Viral Diagnostics Lab: Beating the Next Pandemic KT-1503-01
Electrophoresis Forensics Lab: Wrongfully Convicted? KT-1504-01
Conservation Genetics Lab: Discovering Lemur Diversity KT-1505-01
Dog Genetics Lab: Oodles of Labradoodles™ KT-1506-01
Restriction Digest Analysis Lab: Making the Cut KT-1507-01
DNA Glow Lab™: Exploring DNA Structure KT-1900-01
P51™ Enzyme Lab: β-Gal Glow™ KT-1900-02
P51™ Chlorophyll Lab: A Free Resource KT-1900-03
COVID qPCR Lab: Diagnosing SARS-CoV-2 Infection KT-1900-06
BioBits®: Central Dogma KT-1910-01
BioBits®: Protein Structure and Function KT-1910-03
BioBits®: Modeling Antibiotic Resistance KT-1910-05
Knockout! A CRISPR/Cas Gene Targeting Lab KT-1800-01
Chopped! Using CRISPR/Cas to cut DNA KT-1801-01
 True Blue™ Transformation Lab KT-1802-01

For a detailed list of frameworks and AP Biology science practices that each lab is aligned to, see the Instructor’s Guide for any lab (free to download from each lab’s product page). Here are a few examples some of our most popular labs:

DNA Glow Lab™: Exploring DNA Structure

Move beyond paper models and investigate DNA structure directly! Investigate how DNA sequence, temperature, and pH interact to maintain the structure of the double helix.

Alignment: Unit 1: Chemistry of Life (1.3 Introduction to biological macromolecules; 1.4 Properties of biological molecules; 1.5 Structure and function of biological molecules; 1.6 Nucleic acids)

 Conservation Genetics Lab: Discovering Lemur Diversity

Scientists working in the forests of Madagascar may have rediscovered a species of lemur that was thought extinct. Compare how different types of data (morphological and genetic) can be used to answer questions about species and evolution, build phylogenetic trees, and explore how generalists and specialists fare in face of ecological change.


  • Unit 6: Gene Expression and Regulation (6.8 Biotechnology)
  • Unit 7: Natural Selection (7.6 Evidence of evolution; 7.9 Phylogeny; 7.11 Extinction)
  • Unit 8: Ecology (8.5 Community ecology; 8.6 Biodiversity; 8.7 Disruptions to ecosystems)

miniPCR Sleep Lab™ – Lark or Owl?

Sleep Lab

Participate in an authentic investigation on the genetics of sleep and circadian clocks. Use PCR and gel electrophoresis to determine your own genotype at a locus that has been associated with morning vs. evening preference. Then, use statistics to see if that association holds in your classroom.


  • Unit 4: Cell Communications and Cell Cycle (4.5 Feedback)
  • Unit 5 Heredity (5.3 Mendelian genetics; 5.4 Non-Mendelian genetics; 5.5 Environmental effects on phenotype)
  • Unit 6: Gene Expression and Regulation (6.6 Gene expression and specialization; 6.7 Mutations; 6.8 Biotechnology)

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