Looking for biotechnology labs that align to the AP Biology Frameworks?

Looking for how miniPCR bio Learning Labs align to the AP biology frameworks? Check out our full list of AP Biology-aligned Learning Labs from miniPCR bio™.

Biotechnology may be listed as topic 6.8 in the AP Biology Course and Exam Description, but really, biotechnology is not a standalone unit. Biotechnology is integral to how biologists do science. As you train your AP students to answer biological questions, you want them to use the tools of modern biology!

At miniPCR bio, we offer inquiry-based, hands-on lab investigations for all eight units covered on the AP Biology exam. All our labs invite students to investigate natural phenomena, carry out experiments to test predictions, collect and analyze data, interpret the data to draw conclusions, and develop a scientific claim with the evidence they collected via modern techniques.

To see how our Learning Labs align to the AP Biology units, see the table below. Click on any of the lab titles to learn more about it.

Full list of AP Biology aligned Learning Labs from miniPCR bio 1. Chemistry of Life 2. Cell Structure and Function 3. Cell Energetics 4. Cell Communications and Cell Cycle 5. Heredity 6. Gene Expression and Regulation 7. Natural Selection 8. Ecology
Agricultural Monitoring Lab: A Case Study in Antibiotic Resistance KT-1010-01
Bacterial DNA Barcoding Project: 16S rRNA Amplification Kit KT-1015-01
BioBits®: Central Dogma KT-1910-01
BioBits®: Protein Structure and Function KT-1910-03
BioBits® Antibiotic Resistance KT-1910-06
Chopped! Using CRISPR/Cas to cut DNA KT-1801-01
Conservation Genetics Lab: Discovering Lemur Diversity KT-1505-01
COVID qPCR Lab: Diagnosing SARS-CoV-2 Infection KT-1900-06
DNA Glow Lab™: Exploring DNA Structure KT-1900-01
Dog Genetics Lab: Oodles of Labradoodles™ KT-1506-01
Dye Electrophoresis Lab: Cat Genetics KT-1402-01
Dye Electrophoresis Lab: Mendel's Peas KT-1403-01
Dye Electrophoresis Lab: Princes in the Tower KT-1404-01
eDNA Project: Sampling Soil for Antibiotic Resistance KT-1012-02
Electrophoresis Forensics Lab: Wrongfully Convicted? KT-1504-01
Forensics Lab: Analysis of the D1S80 VNTR KT-1009-01
Genotype to Phenotype: PTC Taster Lab KT-1004-03
GMO Detection Lab KT-1003-01
Knockout! A CRISPR/Cas Gene Targeting Lab KT-1800-01
Knockout! PCR Genotyping Experiment KT-1800-02
miniPCR® Crime Lab: Missy Baker Missing™ KT-1000-03
Mushroom ID Project: Fungal DNA Barcoding Kit KT-1014-01
P51™ Chlorophyll Lab: A Free Resource KT-1900-03
P51™ Enzyme Lab: β-Gal Glow™ KT-1900-02
P51™ qPCR Lab: Principles of Quantitative PCR KT-1900-05
Plant Genetics Lab: Taking Mendel Molecular KT-1011-01
DNA Fingerprinting Lab: Shark Attack! KT-1500-03
Sickle Cell Genetics Lab: Diagnosing Baby Marie™ KT-1502-01
miniPCR Sleep Lab™ – Lark or Owl? KT-1005-01
True Blue™ Transformation Lab: Genetically Engineering Bacteria KT-1802-01
Viral Diagnostics Lab: Beating the Next Pandemic KT-1503-01

For a detailed list of frameworks and AP Biology science practices that each lab is aligned to, see the Instructor’s Guide for any lab (free to download from each lab’s product page). Here are a few examples some of our most popular labs:

DNA Glow Lab™: Exploring DNA Structure

Move beyond paper models and investigate DNA structure directly! Investigate how DNA sequence, temperature, and pH interact to maintain the structure of the double helix.


  • Unit 1: Chemistry of Life (1.3 Introduction to biological macromolecules; 1.4 Properties of biological molecules; 1.5 Structure and function of biological molecules; 1.6 Nucleic acids)
  • Unit 5: Heredity
  • Unit 6: Gene Expression and Regulation

 Conservation Genetics Lab: Discovering Lemur Diversity

Scientists working in the forests of Madagascar may have rediscovered a species of lemur that was thought extinct. Compare how different types of data (morphological and genetic) can be used to answer questions about species and evolution, build phylogenetic trees, and explore how generalists and specialists fare in face of ecological change.


  • Unit 6: Gene Expression and Regulation (6.8 Biotechnology)
  • Unit 7: Natural Selection (7.6 Evidence of evolution; 7.9 Phylogeny; 7.11 Extinction)
  • Unit 8: Ecology (8.5 Community ecology; 8.6 Biodiversity; 8.7 Disruptions to ecosystems)

miniPCR Sleep Lab™ – Lark or Owl?

Sleep Lab

Participate in an authentic investigation on the genetics of sleep and circadian clocks. Use PCR and gel electrophoresis to determine your own genotype at a locus that has been associated with morning vs. evening preference. Then, use statistics to see if that association holds in your classroom.


  • Unit 4: Cell Communications and Cell Cycle (4.5 Feedback)
  • Unit 5 Heredity (5.3 Mendelian genetics; 5.4 Non-Mendelian genetics; 5.5 Environmental effects on phenotype)
  • Unit 6: Gene Expression and Regulation (6.6 Gene expression and specialization; 6.7 Mutations; 6.8 Biotechnology)
  • Unit 7: Natural Selection

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